Ferulic acid yog lub cev ua haujlwm phenolic acid ubiquitously nyob rau hauv cov nroj tsuag. Nws yog khaub lig-txuas nrog polysaccharides thiab lignin los tsim ib feem ntawm cov ntoo phab ntsa ntoo. Nws yog ib qho ntawm ntau cov phenolic acids nyob rau hauv cov zaub mov xws li artichoke, txaij thiab pob kws. Nws tseem yog ib qho ntawm cov khoom xyaw nquag ntawm kev siv tshuaj ntsuab hauv Suav ib txwm muaj xws li Angelica, Cimicifuga thiab Chuanxiong. Ferulic acid yog cov tshuaj tso tawm cov tshuaj phenolic hydroxy methoxylation khoom ntawm caffeic acid 3-txoj hauj lwm. Nws muaj cov kev ua haujlwm antioxidant muaj zog thiab tuaj yeem scavenge ntau cov dawb radicals hauv lub cev, suav nrog hydrogen peroxide, superoxide radicals thiab hydroxyl radicals. , nitrous peroxide, etc.Nws muaj kev tiv thaiv zoo rau cov hlab plawv hlab ntsha, hlab ntsha hauv lub raum, lub raum, thiab lwm yam Thiab nws tuaj yeem siv rau hauv chaw kho mob los kho cov kab mob xws li kab mob ua pa, mob plawv thiab tso zis.
Los ntawm kev kawm ntawm pharmacological mechanism, ferulic acid tuaj yeem cuam tshuam qhov nce ntawm cov mob xws li qog necrosis factor-α (TNF-α) thiab interleukin-1β (IL-1β), thiaj li tiv thaiv cov neurons hauv thaj chaw ischemic. Tus qauv thiab ua haujlwm.Ferulic acid tseem tuaj yeem txo qhov chaw ntawm atherosclerosis los ntawm cov roj (cholesterol) ntau dua, kom lub plawv ua raws thiab lub zog ua haujlwm hauv qab ischemia thiab reperfusion zoo tiv thaiv. Ferulic acid kuj tseem txhim kho reserpine-induced neuropathic mob thiab kev coj tus cwj pwm zoo ib yam li kev nyuaj siab los ntawm kev tswj hwm cov txheej txheem neurotransmitter monoaminergic, qhov chaw tiv thaiv kev tiv thaiv oxidative / tshuaj tiv thaiv kab mob, thiab ua rau cov kabmob ua rau lub hnub ua haujlwm.
Natural ferulic acid tuaj yeem scavenge dawb radicals, txhawb cov khoom tsim cov dawb radical scavenging enzymes, nce kev ua haujlwm ntawm glutathione S-transferase thiab purine reductase, thiab inhibit tyrosinase kev ua haujlwm los tswj tib neeg physiology. Tsis tas li ntawd, ferulic acid yog dav siv hauv kev kho mob plawv yog cov tseem ua cov khoom noj ntawm ntau cov tshuaj suav hauv Suav rau kev txhawb nqa cov ntshav kev thiab tshem tawm cov hnoos qeev. Ferulic acid muaj qee qhov kev tiv thaiv ntawm erythrocyte hemolysis thiab tuaj yeem txo qhov tshwm sim ntawm cov ntshav autooxidation. Nws ua pov thawj tias nws muaj kev tiv thaiv zoo los ntawm kev tiv thaiv ntshav oxidative kev nyuaj siab.
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