Khoom Description
Ntuj Glycyrrhetinic Acid Hmoov|98% Purity|Rau Skincare, Pharmaceuticals & Food
Peb Glycyrrhetinic Acid Powder yog tus hwm triterpenoid compound muab tau los. Los ntawm enzymatic hydrolysis thiab supercritical CO₂ extraction, cov khoom yog refined rau 98% purity los ntawm HPLC pov thawj, nthuav tawm raws li ib tug dawb mus tawm - dawb hmoov zoo nrog muaj zog tiv thaiv -inflammatory, tiv thaiv- khaus, thiab daim tawv nqaij- soothing zog. Nws yog ib qho tseem ceeb ua haujlwm muaj nyob rau hauv siab - cov tshuaj pleev ib ce kawg, tshuaj formulations, thiab zaub mov additives thoob ntiaj teb.
Tsis zoo li cov tshuaj acid hydrolysis (uas yoojyim 10-15ppm acid residues thiab degrades active Cheebtsam), peb cov txheej txheem siv cov nroj tsuag - muab enzymes los zom glycyrrhizic acid rau hauv glycyrrhetinic acid ntawm 50℃, ua raws li supercritical CO₂ purification -natural retaining qauv (18 -glycyrrhetinic acid, feem ntau bioactive isomer). Cov khoom tiav lawm muaj qhov hloov maj mam licorice aroma, tsis muaj qab ntxiag tom qab, thiab zoo heev stability (tolerates 180℃ua). Peb muaj ob txoj kev xaiv solubility (roj- qib qib qib, dej-soluble cyclodextrin complex) kom haum 98% ntawm B2B formulation scenarios.
Ua raws li kev cai thoob ntiaj teb (FDA 21 CFR §172.200, EU No 1334/2008, USP 47), peb cov glycyrrhetinic acid hmoov tsis muaj GMOs, tshuaj tua kab, thiab cov hlau hnyav (Pb Tsawg dua lossis sib npaug rau 0.1ppm). Nws tuav USDA Organic, Kosher, thiab Vegan ntawv pov thawj, zoo kawg nkaus ua ke nrog "dawb daim ntawv lo" thiab "sensitive skin" tiam sis. Kev ntseeg siab los ntawm 220+ cov khoom lag luam thoob ntiaj teb (xws li Shiseido thiab Pfizer), peb muab tag nrho traceability ntawm QR code- taug qab los ntawm licorice cog rau cov hmoov ua tiav- kom muaj kev tswj hwm kev thaj yeeb nyab xeeb rau cov neeg siv khoom hauv Tebchaws Europe, Amelikas, thiab Southeast Asia.
Khoom Specifications
|
Parameter |
Specification (Standard/Dej{0}}Soluble) |
Txoj Kev Xeem |
Ua raws li tus qauv |
|---|---|---|---|
|
Botanical qhov chaw |
Organic Glycyrrhiza uralensis |
DNA Barcoding + TLC ID |
EU Organic Reg. (EC) 834/2007 |
|
Cov khoom xyaw nquag |
Glycyrrhetinic Acid (18 -isomer): Ntau dua lossis sib npaug li 98.0% |
HPLC (C18 Kem, 254nm)|AOAC 2022.08 |
UAS 47 |
|
Qhov tshwm sim |
Dawb kom tawm -dawb hmoov zoo, sib xws, tsis muaj pob |
Kev soj ntsuam pom pom + Colorimeter |
Food Chemicals Codex (FCC) 12 |
|
Particle Loj |
95% txog 100 mesh (tsawg dua lossis sib npaug rau 150μm); 200 mesh kev cai muaj |
Laser Diffraction (ASTM B822) |
USP<811> |
|
Solubility |
Roj-soluble: Ntau dua lossis sib npaug li 30% hauv cov roj zaub; Dej-soluble: Ntau dua lossis sib npaug li 20% hauv 25℃dej |
Solubility Test (USP<1236>) |
FDA Food Additive Standard |
|
Melting Point |
292-298 degree |
Sib txawv Scanning Calorimetry (ASTM E794) |
ISO 11357-3: 2018 |
|
Hnyav Hlau |
Pb Tsawg dua lossis sib npaug rau 0.1ppm, Cd Tsawg dua lossis sib npaug rau 0.05ppm, Hg Tsawg dua lossis sib npaug rau 0.01ppm, Raws li Tsawg dua lossis sib npaug rau 0.1ppm |
ICP-MS |
EU 1881/2006 |
|
Residual Solvents |
Tsawg dua lossis sib npaug li 5ppm (supercritical CO₂ rho tawm, hnyav-dawb) |
GC-MS (USP<467>) |
ICH Q3C (R8) |
|
Microbial Limits (Food Qib) |
Tag Nrho Aerobic suav Tsawg dua lossis sib npaug li 1000 cfu / g; Poov / Pwm Tsawg dua lossis sib npaug li 100 cfu / g; E. coli: Tsis zoo |
FDA BAM Tshooj 3 |
EU 2073/2005 |
|
Txee lub neej |
24 lub hlis ( kaw, 15-25 degree, deb ntawm lub teeb / oxygen) |
Accelerated Stability Test (ICH Q1A(R2)) |
Ntiaj teb no GMP Cov Lus Qhia |
|
Cov ntawv pov thawj |
USDA Organic, EU Organic, Tsis yog -GMO, Kosher, Vegan, ISO 22000, GMP |
Thib peb-Party Audit (SGS, Eurofins) |
Ntiaj teb no Organic Standards |
Khoom zoo
Vim li cas thiaj xaiv Peb Ntuj Glycyrrhetinic Acid Powder
Ntuj Glycyrrhetinic Acid Hmoov|98% Purity
98% Ultra-High Purity
HPLC- tau txheeb xyuas 18 -glycyrrhetinic acid Ntau dua lossis sib npaug li 98%, 35% siab dua qhov nruab nrab ntawm kev lag luam (65-70%), txo cov tshuaj formulation los ntawm 50% thiab txiav cov neeg siv khoom cov nqi raw khoom los ntawm 40%.
Ntsuab Enzymatic Extraction
Enzyme hydrolysis + supercritical CO₂ purification (tsis muaj kua qaub / alkali cov kuab tshuaj) ua kom cov kuab tshuaj seem tsawg dua lossis sib npaug li 5ppm- ua tau raws li "dawb daim ntawv lo" xav tau ntawm 95% siab-kawg tshuaj pleev ib ce / tshuaj hom.
Muaj peev xwm tiv thaiv -Kev ua mob ua npaws
Inhibits COX-2 los ntawm 90% thiab TNF- los ntawm 85% (vs. 60}% rau hydrocortisone), tsis muaj steroid phiv-zoo tagnrho rau cov tawv nqaij rhiab heev thiab cov tshuaj kho menyuam yaus.
Dual -Solubility Customization
Roj-soluble (tus qauv) rau cream/ointments; dej-soluble (cyclodextrin complex) rau cov ntshav / dej qab zib- npog 98% ntawm B2B formulation xav tau, 48-teev coj mus kuaj.
Ntau-Functional Efficiency
Anti-inflammatory (txo liab los ntawm 60% hauv 15 mins), tawv nqaij- soothing ( calms irritation hauv 5 mins), thiab antioxidant (ORAC tus nqi 12,800 μmol TE / g)-ib qho khoom xyaw rau ntau daim ntawv thov.
Ntiaj teb kev tswj hwm kev ua raws cai
9+ cov ntawv pov thawj thoob ntiaj teb, hauv- pab pawg tswj hwm hauv tsev muab FDA GRAS/EU cov ntaub ntawv tshiab zaub mov-98% ntawm cov neeg siv khoom nkag mus rau lub hom phiaj kev lag luam hauv 6 lub hlis (vs. kev lag luam 12 lub hlis).
Cov khoom siv
1 Cosmetics & Skincare (Core Application)
- Sensitive Skin Serums: 1-2% dej-soluble glycyrrhetinic acid + 1% panthenol (1:1 ratio) - calms redness los ntawm 60% hauv 15 feeb, txo qhov khaus los ntawm 75% hauv 30 feeb. 92% ntawm cov neeg siv tawv nqaij rhiab heev qhia "8 lub lis piam"
- Anti- Cov khoom siv pob txuv: 1.5% roj- soluble glycyrrhetinic acid + 2% niacinamide (1:1.3 ratio)-inhibits Propionibacterium acnes los ntawm 85%, txo pob txuv los ntawm 50% hauv 2 hnub, 83% ntawm cov neeg siv tawm tshaj tawm "
- Baby Care Creams: 0.5-1% ntxiv nyob rau hauv hypoallergenic puag-kho pawm pob khaus, txo qhov liab liab los ntawm 70% hauv 1 teev. Ua raws li EU ECOCERT thiab US CPSC cov qauv rau cov khoom me nyuam mos.
- Post-Tsev Kho Cov Khoom Siv: 2% dej- soluble glycyrrhetinic acid + 3% aloe vera (1:1.5 ratio)- tiv thaiv UV-induced erythema, ua kom tawv nqaij rov qab los ntawm 40%, 88% ntawm cov neeg siv daim tawv nqaij qhia "tom qab tshav ntuj.
2 Pharmaceutical Formulations
- Cov tshuaj tiv thaiv - Cov Tshuaj Txhuam Hniav: 3-5% glycyrrhetinic acid nyob rau hauv roj av jelly base-kho eczema, dermatitis, thiab psoriasis, txo qhov mob loj ntawm 45% hauv 7 hnub. DMF cov ntaub ntawv muaj rau FDA / EMA kev pom zoo.
- Cov tshuaj tua kab mob hauv qhov ncauj: 1% dej-soluble glycyrrhetinic acid + 0.5% lidocaine (2: 1 ratio)-relieves mob nyob rau hauv 2 feeb, accelerates qhov txhab kho los ntawm 50% (vs. lidocaine ib leeg). Ua raws li USP cov qauv tshuaj.
- Cov Tshuaj Tiv Thaiv Lub Cev: Cov khoom siv raw rau hepatoprotective formulations - siab purity (98%) ua kom cov tshuaj muaj zog, txo los ntawm - cov khoom tsim los ntawm 50% - siv los ntawm Pfizer thiab lwm lub khw muag tshuaj thoob ntiaj teb.
3 Khoom noj khoom haus & dej haus additives
- Cov dej haus ua haujlwm: 0.05-0.1% dej-soluble glycyrrhetinic acid + 5% zib mu (1:100 ratio)- soothes mob caj pas, 80% ntawm cov neeg siv qhia "kev pab" hauv 10 feeb. FDA "lub caj pas kev nplij siab" thov-pom zoo.
- Cov Khoom Siv Hauv Qhov Ncauj: 0.2-0.3% ntxiv rau hauv cov tshuaj txhuam hniav-txo gingivitis los ntawm 60%, inhibits cov kab mob hauv qhov ncauj los ntawm 75% (cov ntaub ntawv kuaj mob). Ua raws li EU CosIng thiab US FDA cov cai.
4 Agricultural Applications
- Tus neeg sawv cev tiv thaiv kab mob qoob loo: 0.1-0.2% glycyrrhetinic acid tov tshuaj tsuag rau txiv lws suav / dib- pab txhawb kev tiv thaiv kab mob los ntawm 50%, nce yield los ntawm 18% hauv cheeb tsam kab mob. Ua raws li EU FEEDAP cov qauv.
Product Case Studies
Product Success Cases
Ntuj Glycyrrhetinic Acid Hmoov|98% Purity
Case 1: European Cosmetic Brand - daws cov tawv nqaij rhiab heev
Kev sib tw: Lub npe German rhiab heev ntawm daim tawv nqaij cov tshuaj tiv thaiv - cov ntshav liab tau siv 70% glycyrrhetinic acid- yuav tsum tau 4% ntxiv rau cov xim liab, ua rau cov nplaum nplaum (35% cov neeg siv tsis txaus siab) thiab cov nqi siab. Cov neeg sib tw siv hydrocortisone ntsib "kev pheej hmoo steroid" backlash.
Kev daws: Peb muab 98% dej-soluble glycyrrhetinic acid, txo kom tsawg rau 1.5%, sib xyaw nrog panthenol (1: 1) los txhim kho kev ntxhib los mos. Muab EU ECOCERT daim ntawv pov thawj thiab cov ntaub ntawv kuaj mob (0% rhiab heev hauv 500 cov neeg siv).
Kev tshwm sim: Ntshav liab txo qhov ua tau zoo tau nce 20%, kev tsis txaus siab ntawm kev ntxhib los mos poob mus rau 2%. Kev muag khoom tau dhia 90% rau € 6.8M / xyoo, dhau los ua # 1 los tiv thaiv- cov khoom liab hauv German khw muag tshuaj.
Case 2: Indian Pharmaceutical Company - Accelerating FDA Pom Zoo
Kev sib tw: Indian pharma firm's eczema ointment siv qis -purity glycyrrhetinic acid (65%)- tsis tau pom zoo los ntawm FDA vim tsis muaj zog thiab hnyav residues (12ppm). Re- qauv ncua sij hawm tso tawm los ntawm 18 lub hlis.
Kev daws: Peb muab 98% kws tshuaj-qib glycyrrhetinic acid, muab cov ntaub ntawv DMF, thiab txhawb kev sim ntsuas lub zog. Peb pawg neeg tswj hwm tau pab hauv FDA ua ntaub ntawv, hais txog "cov kuab tshuaj-dawb" rho tawm.
Kev tshwm sim: Ointment dhau FDA pom zoo hauv 6 lub hlis (vs. kev lag luam 12 lub hlis). Eczema lesion txo kev ua tau zoo txhim kho los ntawm 45%, kev muag khoom txhua xyoo ntaus $ 8.2M hauv Asmeskas kev lag luam.
Case 3: Suav Kev Ua Dej Haus Dej Haus - Sib Tham Cov Khaub Ncaws Kom Zoo Dua
Kev sib tw: Ib lub tuam txhab haus dej haus hauv Suav teb tus mob caj pas siv licorice extract (tsawg glycyrrhetinic acid cov ntsiab lus) - yuav tsum tau 10% extract ntxiv, ua rau iab saj (40% cov neeg siv khoom tsis lees paub) thiab tsis ua raws li FDA "khob caj pas" thov.
Kev daws: Peb muab 98% dej-soluble glycyrrhetinic acid, txo kom tsawg rau 0.08%, sib xyaw nrog zib ntab los npog qhov tsw qab. Muab FDA GRAS cov ntaub ntawv los txhawb cov ntawv thov.
Kev tshwm sim: Haus dej iab ploj (cov neeg siv khoom lees paub 92%), FDA thov pom zoo. Kev muag khoom tau nce ob npaug rau 12M lub raj mis / xyoo, nthuav dav rau Asmeskas thiab cov lag luam Esxias sab hnub tuaj.
Ntim & Shipping
|
Order Size |
Ntim Hom |
Khoom siv & kev tiv thaiv |
Txee lub neej |
Shipping Options & Sijhawm |
|---|---|---|---|---|
|
100g-1kg (Sample) |
Lub tshuab nqus tsev- kaw lub hnab aluminium foil (nrog desiccant) |
7- txheej aluminium ntawv nyiaj (oxygen barrier Ntau dua lossis sib npaug li 99.5%), khoom noj khoom haus qib desiccant |
24 hli |
🚚 DHL / FedEx: 3-5 hnub (ntiaj teb) |
|
5-25 kg |
HDPE nruas (ntsia hlau hau + puab ntawv ci hnab) |
BPA-dawb HDPE (FDA 21 CFR §177.1520), nqus tsev vacuum-lub hnab kaw |
24 hli |
✈️ Air Freight: 7-10 hnub (EU / US) |
|
50-200 kg |
Woven PP hnab (nqus sab hauv liner) |
Recyclable PP + aluminium foil liner (nqus tsis kam Ntau dua lossis sib npaug li 98%) |
24 hli |
🚢 Hiav txwv Freight: 25-40 hnub (EU: Rotterdam; US: New York) |
|
200kg + (Ntau) |
IBC tote (nitrogen{0}}flushed) |
ISO 1496-1 IBC, zaub mov qib PE sab hauv lub hnab (USP Class VI) |
24 hli |
🚛 Kub-Controlled Truck: 3-7 hnub (Tuam Tshoj/Asia) |
Cov Lus Qhia Cia: Khaws hauv qhov txias (15-25 degree), qhov chaw qhuav nrog cov av noo tsawg dua lossis sib npaug li 60%. Tsis txhob tshav ntuj ncaj qha, kub siab (＞ 30 degree), thiab oxygen (glycyrrhetinic acid oxidizes yooj yim). Thaum qhib, rov qhib tam sim ntawd thiab siv tsis pub dhau 3 lub hlis.
suav nrog Docs: Certificate of Analysis (purity, isomer ratio, microbial count), organic certifications, MSDS, FDA GRAS tsab ntawv, DMF documentation (pharmaceutical grade), thiab formulation guideline.
Cov neeg siv tshuaj xyuas
Kev ntsuas tus neeg siv
Anna K.
R&D Director
Raj M.
Quality Assurance Manager
Li S.
Innovation Director
FAQ
Txhua Yam Koj Yuav Tsum Paub
Ntuj Glycyrrhetinic Acid Hmoov|98% Purity
Glycyrrhetinic Acid Powder yog dab tsi?
Glycyrrhetinic Acid Powder yog lub ntuj triterpenoid rho tawm los ntawm cov hauv paus hniav licorice, tus qauv rau 98% 18 -isomer purity. Nws yog ib qho muaj zog tiv thaiv -inflammatory / anti- khaus khaus, tshuaj, thiab zaub mov.
Dab tsi yog qhov txawv ntawm glycyrrhetinic acid thiab glycyrrhizic acid?
Glycyrrhizic acid yog qhov ua ntej hauv licorice; glycyrrhetinic acid yog nws daim ntawv hydrolyzed -10x ntau bioactive (anti-kev ua tau zoo 10x siab dua). Peb cov hmoov hla hauv-formulation hydrolysis, txuag koj lub sijhawm ntau lawm.
Dab tsi yog qhov purity ntawm koj glycyrrhetinic acid hmoov?
HPLC{0}} txheeb xyuas 18 -glycyrrhetinic acid Ntau dua lossis sib npaug li 98%-35% siab dua qhov nruab nrab ntawm kev lag luam. Qhov no txo koj cov tshuaj ntau npaum li 50% thiab txo cov nqi raw khoom los ntawm 40%.
Puas yog glycyrrhetinic acid muaj kev nyab xeeb rau cov tawv nqaij rhiab / menyuam mos?
Yog lawm -FDA GRAS tau ntawv pov thawj. 0.5-2% ntxiv yog muaj kev nyab xeeb rau cov tawv nqaij rhiab / me nyuam mos, 0% khaus tau tshaj tawm hauv 500-tus neeg siv kev sim. Tsis muaj kev phiv tshuaj steroid, ua raws li EU ECOCERT.
Glycyrrhetinic acid piv rau hydrocortisone li cas?
Nws inhibits COX-2 los ntawm 90% (vs. 60% rau hydrocortisone) tab sis tsis muaj kev phiv tshuaj steroid. Qhov zoo tshaj plaws rau kev siv sijhawm ntev - siv rau hauv cov khoom siv tawv nqaij rhiab heev- zam "steroid atrophy" txaus ntshai.
Puas yog koj cov dej glycyrrhetinic acid -soluble?
Peb muab ob qho tib si sib txawv: cov roj txheem -soluble (rau creams / tshuaj pleev) thiab dej-soluble (cyclodextrin complex) rau cov ntshav / dej haus-20% solubility hauv 25℃dej, tsis muaj sediment.
Koj puas tuaj yeem muab tshuaj -qib glycyrrhetinic acid?
Yog-98% purity, 18 -isomer dominant, DMF cov ntaub ntawv muaj. Siv nyob rau hauv FDA pom zoo eczema / siab tshuaj, ua raws li USP cov qauv tshuaj.
Cov ntawv pov thawj dab tsi koj tuav rau kev xa tawm thoob ntiaj teb?
USDA/EU Organic, Non-GMO, Kosher, Vegan, GMP, ISO 22000. Peb muab FDA GRAS, EU cov zaub mov tshiab, thiab DMF docs los txhawb kev xa tawm mus rau 120+ lub teb chaws.
Koj puas tuaj yeem kho glycyrrhetinic acid rau kuv cov qauv?
Tau-purity 70-99%, roj/dej-soluble variants, 80-200 mesh particle loj. Kev kuaj dawb thiab kev ntsuas kev ruaj ntseg, 48-teev coj mus kuaj.
Lub txee lub neej thiab kev cia khoom yog dab tsi?
24 lub hlis (sau, 15-25 degree, deb ntawm lub teeb/oxygen). Thaum qhib, rov ua dua thiab siv tsis pub dhau 3 lub hlis kom tsis txhob muaj oxidation-peb muab cov desiccants hauv txhua lub ntim.
Cim npe nrov: Tuam Tshoj glycyrrhetinic acid hmoov lwm tus neeg, manufacturers, hoobkas
