Khoom Description

Parthenolide yog cov tshuaj sib xyaw ua ke los ntawm Pyrethrum parthenium (L.) JGSm. Feverfew Extract Parthenolide hmoov yog ib yam khoom ntuj tsim los ntawm sesquiterpene lactones, cais los ntawm cov nroj tsuag tshuaj xws li Aiju thiab Sightseeing Tsob Ntoo, uas yog dav siv nyob rau hauv kub taub hau, deworming, thiab anti-inflammatory teebmeem. Nyob rau hauv xyoo tas los no, cov kev tshawb fawb tau lees paub tias paeonolactone muaj ntau yam kev ua haujlwm tseem ceeb hauv tshuaj, xws li tshuaj tiv thaiv qog, tiv thaiv kab mob, tiv thaiv kab mob thiab tiv thaiv atherosclerosis. Kev lig kev cai, paeonolactone feem ntau yog siv los kho mob migraine, kub taub hau thiab mob caj dab rheumatoid.

Khoom npe	Parthenolide hmoov
Qhov tshwm sim	Dawb hmoov
Specification	Parthenolide: Ntau dua lossis sib npaug li 98% (HPLC); 0.3%-3%, 99% HPLC Parthenolides
Qib	Qib zaub mov
Qhov chaw	Chrysanthemum parthenium (paj)
Daim ntawv thov	Tshuaj, Khoom noj khoom haus additive, Dej haus, Cosmetic Field, thiab Healthcare Products
Daim ntawv pov thawj	HACCP, ISO, QS, Halal, Kosher, FDA, COSMOS, IFS, BRC
Zoo	Tsis-GMO, Tsis-irradiation, Allergen Dawb, BSE / TSE Dawb

Basic Analysis

Yam khoom	Specification	Xaus
Purity (HPLC)	Parthenolide: Ntau dua lossis sib npaug li 98%	100%
Qhov tshwm sim	Dawb hmoov	Ua raws
Hnyav hlau
Tag nrho cov hlau	Tsawg dua los yog sib npaug rau 10.0ppm	Ua raws
Coj	Tsawg dua lossis sib npaug rau 2.0ppm	Ua raws
Mercury	Tsawg dua los yog sib npaug rau 1.0ppm	Ua raws
Cadmium	Tsawg dua los yog sib npaug rau 0.5ppm	Ua raws
Poob rau ziab	Tsawg dua los yog sib npaug rau 0.5%	0.5%
Kab mob
Tag nrho cov kab mob	Tsawg dua lossis sib npaug li 1000cfu / g	Ua raws
Poov xab	Tsawg dua lossis sib npaug li 100cfu / g	Ua raws
Escherichia coli	Tsis suav nrog	Tsis suav nrog
Salmonella	Tsis suav nrog	Tsis suav nrog
Staphylococcus	Tsis suav nrog	Tsis suav nrog

Nta

Parthenolide muaj ntau yam kev tshaj tawm hauv vitro lom cov dej num, suav nrog:

• Inhibition ntawm HDAC1 protein yam tsis muaj kev cuam tshuam rau lwm chav kawm I/II HDACs, uas ua rau muaj kev cuam tshuam DNA kev puas tsuaj hauv qee lub hlwb (yuav tsum tau muaj apoptosis).
• Kev hloov kho ntawm NF-κB-mediated inflammatory teb nyob rau hauv kev sim atherosclerosis.
• Inducing apoptosis nyob rau hauv mob myelogenous leukemia (AML) hlwb, ua rau cov pob txha pob txha ib txwm tsis raug mob. Tsis tas li ntawd, qhov sib xyaw ua ke tuaj yeem tau txais ntawm cov hauv paus hniav vim tias nws kuj tua cov qia hlwb uas ua rau AML.
• Kev tawm tsam Leishmania amazonensis.
• Kev ua haujlwm ntawm microtubule-interfering.
• Agonist ntawm adiponectin receptor 2 (AdipoR2).
• Inhibition ntawm mammalian thioredoxin reductase.

Daim ntawv thov

(1) Siv nyob rau hauv kev lag luam teb ua tshuaj raw khoom;
(2) Siv rau hauv cov khoom kho mob;
(3) Siv rau hauv cov zaub mov thiab dej-soluble dej haus.

(4) Siv rau hauv cov khoom siv tshuaj pleev ib ce.